Synthesis, photosensitization and antimicrobial activity evaluation of some novel Merocyanine dyes

H. A. Shindy , A. K. Khalafalla, M. M. Goma and A. H. Eed

Abstract

Novel acyclic and cyclic merocyanine dyes derived from the nucleu of furo [(3,2-d) pyrazole; (3,2 d )imidazole]were prepared. The electronic visible absorption spectra of all the synthesized new cyanine dyes were examined in 95% ethanol
solution to evaluate their photosensitization properties. Antibacterial and antifungal activities for some selected dyes were tested against various bacterial and fungal strains (Escherichia coli, Staphylococcus aureus, Aspergillus flavus and
Candida albicans) to evaluate their antimicrobial activity. Structural identification was carried out via elemental analysis, visible spectra, IR and 1H NMR spectroscopic data.