11. Issue 3

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Mohammad Asif. Effects of some antiepileptic drugs on reproductive system. Current Science Perspectives 3(3) (2017) 105-123


Epilepsy is associated with reproductive disorders and decreased fertility. Some studies were evaluated on reproductive system, the effects of antiepileptic drug on women and on male fertility. Reproductive disorders were more common in women with idiopathic generalized epilepsy and in women taking valproate also in young age increased the risk of these disorders. Oxcarbazepine was associated with reproductive disorders in women with epilepsy. In men all antiepileptic drugs were associated with sperm abnormalities, and sperm abnormalities in men taking valproate were associated with decreased testicular volume. The epilepsy and antiepileptic drugs during adulthood decreased fertility. The reproductive endocrine effects of AEDs should be taken into consideration when prescribed to fertile aged men and women, especially, if the duration of treatment is long.



    Hari Singh Prajapati, Savita Vyas and Mukesh Pandey. Biomass and potential applications: A case study from Madhya Pradesh, India. Current Science Perspectives 3(3) (2017) 124-127


At present biomass is one of the most potential source of energy in the world, hence it may become the primary source of energy. In this paper we were assessing the potential of biomass in Madhya Pradesh and conversion of biomass to energy and future prospects and its various applications including power generation through gasification, It includes low, medium and large-scale power generation and various applications were discussed.


    Hamdy A. Shaaban and Shimaa A. Moawad. Chemical composition, nutritional and functional properties of some herbs and spices. Current Science Perspectives 3(3) (2017) 128-142.


A comprehensive study was carried out to assess the microbiological, nutritional, biochemical and essential oil characteristics of three Egyptian traditional cultivars seeds,  namely, cumin (Cuminum cyminum) and coriander (Coriandum sativum) spices as well as for basil whole herb (Ocimum basilicum) collected from different Egyptian export centers as being ready for export. The found values for humidity in dry seeds of cumin (7.4%) and coriander (6.4%) as well as total ash and ash insoluble in acid (in cumin 7.7% and 0.74%, but in coriander 5.3% and 0.55%, respectively) were lower than the maximum limits indicated by the Egyptian Specification Standards (ES) and by International Standards Organization (ISO) for cumin and coriander seeds. Analysis of essential minerals in seed spices and herbs indicated that they were are rich in K, Ca, Na, Fe and Zn. Total bacterial count was low content in seeds of cumin and coriander as well as fresh whole basil herb. The microbiological load in all tested seed spices and herbs was found lower than those indicated by the ES and ISO for cumin and coriander seeds. Yields in hydrodistilled essential oils (EOs) were the highest in cumin seeds (3.762%), while both coriander and basil herb had lower amounts (0.285% and 0.686%, respectively). EOs contents were found higher than the maximum limits for cumin (1.5% - 2.5% on dry weight basis), but the within the limits for coriander (0.1% - 0.5% on dry weight basis) as indicated by the ES and ISO for cumin and coriander seed oils. Gas chromatogra-phy of extracted EOs from seeds of cumin and coriander as well as basil herbs indicated the presence of 41, 35 and 47 compounds, respectively, where cuminaldehyde was the major component in cumin volatiles, but was linalool in volatiles of both coriander seeds and basil herbs. EOs of basil herbs grown in Egypt, were of the high linalool -chemotype which were characterized by high con-tents of linalool and relatively lower amounts of eugenol. However, the major compounds in the three tested EOs from seeds or herbs grown in Egypt are in accordance with literature reports from different parts of the world. Volatile oil components in EOs of the three tested Egyptian spices and herbs were classified into groups, based on the relative area (%). The proportion of the major and the other main components in EOs from seeds of cumin and coriander cultivars were within the ranges indicated by both the ES and ISO for cumin seed oils (cuminaldehyde between 15% - 46%) and for coriander seed oils (linalool between 65% - 78%). The aim of the present work was to Assessment study certain commonly used Egyptian spice and herbal products for characterizing their physical, biochemical and microbiological properties.




Mohandas Mangre, Savita Vyas and Mukesh Pandey. Downdraft fixed bed biomass gasifier: A review. Current Science Perspectives 3(3) (2017) 143-147


Biomass gasifier is one of the promising technologies to fulfill the energy demand of India as well as world. It also significantly reduces biomass waste generated in developing countries. Biomass gasification is a chemical process that converts solid biomass into useful convenient gaseous fuel. In this paper, various aspects of research and modification in downdraft fixed bed gasifier system and parameters like equivalence ratio, operating temperature, moisture content, superficial velocity, residence time etc. are reviewed. Various applications and status of biomass and gasification are discussed.




Mbatchou Valentine Chi, Kanwugu Osman Nabayire and Yesman Akuoko. Vernonia amygdalina Leaf:  Unveiling its antacid and carminative properties In Vitro. Current Science Perspectives 3(3) (2017) 148-155


Leaves of Vernonia amygdalina commonly known as bitter leaf is widely consumed in the sub-Saharan regions of Africa. This study therefore considers the properties of leaves of the plant as alternative sources of an antacid and carminative drug. Bioactive compounds were extracted separately with methanol and distilled water. The neutralizing capacity, duration of neutralizing effects and amounts of carbon dioxide evolved in the antacid and carminative studies respectively were determined for both aqueous and methanol leaf extracts. Aqueous leaf extract showed a significant antacid and carminative potential (P < 0.05) when compared with the methanolic leaf extract at all the tested concentrations. The highest neutralizing effect and duration of neutralizing effect obtained for the aqueous leaf extract were 2.24 ± 0.000 and 162.56 ± 0.087 minutes respectively as against 1.97 ± 0.007and 95.55 ± 0.083 minutes of the methanolic leaf extract. Further evidence is provided in the high neutralizing capacity of the aqueous leaf extract (34.93 ± 0.088mL) compared to that of the methanolic extract (7.80 ± 0.115mL).  Higher doses of the aqueous leaf extract were however needed for comparable results with the control Gastrone® (13.5252g of aqueous extract ≡ ~3.1582g of Gastrone® (antacid); 5.3797g of aqueous extract ≡ ~3.1582g of Gastrone® (carminative).   Scientific data in this research work therefore supports the local use of aqueous leaf extract of Vernonia amygdalina  as an antacid and carminative agent by the people of Tamale, Northern region, Ghana.