Simple synthesis of some new heterocyclic derivatives incorporation coumarin -2- one moiety

H. A. Latif and E. A. Elrady

Abstract

3-(1-ethoxy-3-oxo-3-phenylpropyle-1-enyl)-2H-coumarin-2-one (2), had been synthesized and reacted with some selected reagents such as hydrazine hydrate, urea, cyanoacetamide, cyanoacetohydrazide, orthophenylene diamine, orthoaminophenol and 5-aminotriazole in ethanol piperidine solution to afford new multisubtituted 3-(pyrazol, pyrimidine, pyridine, diazepine, oxazepin, triazol)- 2H- coumarin-2-one derivatives.