Nutra-pharmaceutical efficacy appraisal of Lavandula stoechas leaves extracts in different solvents

Asad Rauf, Syeda Mona Hassan and Sania Rafique

Abstract

Present study was conducted to determine the antioxidant and antibacterial properties of L. stoechas leaves. Four solvents (80% methanol, 80% ethanol, 100% methanol and 100% ethanol) were used to extract the phytochemical, antifungal, and antioxidant components of L. stoechas leaves. In an 80% methanolic solvent, L. stoechas Leaves produced the highest extract yield (40.1 g/100g DW). Antioxidant examination of L. stoechas Leaves extracts in terms of total phenolic and total flavonoid contents revealed that the 80% methanolic extract had higher total phenolic content (33.2 mg GAE/g DW), as well as the higher total flavonoid content (46.5 mg CE/g DW. The DPPH radical scavenging activity and reduction power were used to assess antioxidant capacity. According to the findings, the 80% methanolic extract showed low potential and strong radical scavenging activity. The antimicrobial properties of L. stoechas leaves were determined by disc diffusion method. The antibacterial and antifungal potential of 80% methanolic extract against E. coli (30 mm DIZ) and A. Paraciticus (29 mm DIZ), respectively was observed. The results showed that 80% methanolic L. stoechas Leaves extract are potent source of nutra-pharmaceuticals agents for practical applications.