Pharmacological potential of pomegranate: Natural remedy for metabolic disorders and therapeutic innovation

Kashifa Jalil, Shahzaib Khurshid, Muhammad A. Ashraf, Muhammed J. Akhtar, Naveed Ahmad and Munawar Iqbal

Abstract

The growing interest in the pharmaceutical applications of pomegranate (P. granatum) stems from its remarkable potential in developing medicinal drugs and dietary supplements aimed at addressing a wide range of health conditions. Pomegranate is rich in bioactive polyphenols, including flavonoids, phenolic acids, and tannins, contributing to its diverse therapeutic properties. Numerous studies have demonstrated its antioxidant, antibacterial, anti-inflammatory, anti-obesity, cardioprotective, glucose-regulating, anti-arthritic, nephroprotective, and anti-cancer benefits. Additionally, pomegranate has shown promise in food preservation and quality enhancement. These findings are invaluable to pharmacology, as they provide a foundation for developing novel therapeutic agents to combat metabolic disorders and related health issues. This review underscores the significant potential of pomegranate-derived products in drug discovery and pharmacological innovation. The remarkable therapeutic potential of pomegranate and its bioactive components offers a promising avenue for the development of innovative pharmacological solutions and functional food products.